Chemical characterization of the tinctures and dry extracts of medicinal plants of the Cerrado by thin layer chromatography

Authors

  • Maria Mercedes Alves Unaerp
  • Ana Maria Soares Pereira UNAERP
  • Paulo Sérgio Pereira UNAERP
  • Suzelei Castro França UNAERP
  • Bianca Waléria Bertoni UNAERP

Keywords:

Quality Control, Cerrado, Phytochmistry Natural Products, Seasonality

Abstract

Medicinal plants endemic to the Cerrado biome are widely used in the form of tinctures and extracts, but analytical methods to validate those pharmaceutical formulations are still scarce. The aim of this study was to identify chemical markers to investigate the seasonal influence on the chemical composition of dyes and extracts of 20 species endemic to the Cerrado biome. Dried hydroalcoholic extracts and dyes were analyzed by comparative thin-layer chromatography (CCDC) on silica gel F254 plates using 11 specific chemical markers. The retention factor (Rf) of chemical markers was used as reference for
identifying the substances present in the investigated samples. For most of the studied species, extracts of plants collected during the dry season showed higher yieldsand flavonoids were the most frequent compounds found in the tinctures and extracts. Only the extracts and tinctures of Achyrocline
satureoides, Lychnophora ericoides and Zeyheria montana showed distinct chemical profile considering the harvest season. The methodology used was efficient and proper to establish the chemical quality control of medicinal plant species from the Cerrado.

Author Biographies

Maria Mercedes Alves, Unaerp

Departamento de Biotecnolgia

Ana Maria Soares Pereira, UNAERP

Departamento de Biotecnolgia

Paulo Sérgio Pereira, UNAERP

Departamento de Biotecnolgia

Suzelei Castro França, UNAERP

Departamento de Biotecnolgia

Bianca Waléria Bertoni, UNAERP

Departamento de Biotecnolgia

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Published

2012-01-16

How to Cite

Alves, M. M., Soares Pereira, A. M., Pereira, P. S., Castro França, S., & Bertoni, B. W. (2012). Chemical characterization of the tinctures and dry extracts of medicinal plants of the Cerrado by thin layer chromatography. Scientia Plena, 7(12). Retrieved from https://scientiaplena.org.br/sp/article/view/159

Issue

Vol. 7 No. 12 (2011): December/Dezembro 2011

Section

Articles

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