Antimicrobial activity of biosurfactant produced by Pseudomonas sp. CCMICS 105

Authors

  • Thalyta Silva Oliveira Universidade Federal do Sul e Sudeste do Pará
  • Sidnei Cerqueira dos Santos Universidade Federal do Sul e Sudeste do Pará https://orcid.org/0000-0003-1169-256X
  • Sebastião da Cruz Silva Universidade Federal do Sul e Sudeste do Pará
  • Ana Cristina Viana Campos Universidade Federal do Sul e Sudeste do Pará

DOI:

https://doi.org/10.14808/sci.plena.2022.016201

Keywords:

antibiotic, rhamnolipid, pathogenic microorganisms

Abstract

The irrational and inappropriate use of antibiotics has provided favorable conditions to trigger the resistance of microorganisms. Biosurfactants have shown promising pharmaceutical properties, mainly related to their antimicrobial function. In this sense, the aim of this work was to evaluate the antimicrobial activity of biosurfactant produced by Pseudomonas sp. CCMICS 105 against pathogenic microbial strains. The production of the biosurfactant was carried out in a mineral saline medium and the surfactant was extracted with a mixture of chloroform and ethanol solvents. The antimicrobial activity was evaluated against Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Candida albicans strains, using the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) tests. The biosurfactant produced by the bacterial strain inhibited all strains tested, showing equivalent results for MIC and MBC. The prospect of biosurfactant with antimicrobial potential is an alternative for discovering new antibiotics.

Author Biographies

Thalyta Silva Oliveira, Universidade Federal do Sul e Sudeste do Pará

Graduada em Ciências Biológicas, Faculdade de Biologia, Instituto de Estudos em Saúde e Biológicas, Universidade Federal do Sul e Sudeste do Pará.

Sidnei Cerqueira dos Santos, Universidade Federal do Sul e Sudeste do Pará

Doutor em Biotecnologia. Professor Adjunto do curso de Ciências Biológicas do Instituto de Estudos em Saúde e Biológicas da Universidade Federal do Sul e Sudeste do Pará. Atua na área de Biotecnologia, Microbiologia e Propriedade Intelectual. Endereço para acessar este CV: http://lattes.cnpq.br/5913484433989475

Sebastião da Cruz Silva, Universidade Federal do Sul e Sudeste do Pará

Professor Adjunto da Universidade Federal do Sul e Sudeste do Pará. Doutor em Química pela Universidade Federal de São Carlos (UFSCar)

Ana Cristina Viana Campos, Universidade Federal do Sul e Sudeste do Pará

Professora Adjunta da Universidade Federal do Sul e Sudeste do Pará. Doutora em Odontologia pela Faculdade de Odontologia, Universidade Federal de Minas Gerais (UFMG).

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Published

2022-02-17

How to Cite

Silva Oliveira, T. ., Santos, S. C. dos, da Cruz Silva, S. ., & Viana Campos, A. C. . (2022). Antimicrobial activity of biosurfactant produced by Pseudomonas sp. CCMICS 105. Scientia Plena, 18(1). https://doi.org/10.14808/sci.plena.2022.016201

Issue

Vol. 18 No. 1 (2022): Janeiro/January 2022

Section

Articles

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Copyright (c) 2022 Thalyta Silva Oliveira, Sidnei Cerqueira dos Santos, Sebastião da Cruz Silva, Ana Cristina Viana Campos

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