TY - JOUR AU - Silva, Robson Amaro Augusto da AU - Group, Studant AU - Amarim, Maise Mendonça AU - Figueiredo, Tiana Baqueiro AU - Gestinari, Raquel de Souza AU - Tomazi, Laize PY - 2016/09/27 Y2 - 2024/03/28 TI - Sickle Cell Anemia in the Boqueirão Kilombo Community, Bahia, Brazil JF - Scientia Plena JA - Sci. Plena VL - 12 IS - 9 SE - DO - 10.14808/sci.plena.2016.091002 UR - https://scientiaplena.org.br/sp/article/view/2920 SP - AB - <p>Sickle cell anemia (SCA) is the most common monogenic hereditary disease in Brazil. The North and Northeastern regions of Brazil concentrate a large number of outstanding African ancestry communities, denominated kilombo. The aim of this study was to make a survey of SCA cases in the Boqueirão Kilombo community, situated in Bahia semi-arid region. Individuals from the 467 who replied positively for the occurrence of jaundice, and family history of sickle cell anemia were pre-selected to undergo the diagnostic exam for sickle cell anemia and included in the Group 1. The others individuals were included in the Group 2. Blood samples evaluation of Group 1 showed the following hemoglobin genotypes: HbAA in 65 individuals, HbSS in 3 individuals and HbAS in 29 individuals, HbAF in 1 individual and HbAC in 2 individuals. One of the individuals with SCA and all the heterozygots for the mutated allele S did not know that they had the mutation. The survey data demonstrate the need for health assistance directed towards these special communities.</p> ER -